Trip Highlights

  • For foodies: enjoy a private food tour of Lima
  • Get up close to wildlife in a dug-out canoe in the Amazon
  • Connect with an Andean community in the Sacred Valley
  • A thrilling 4×4 adventure across the salt flats of Bolivia
  • Red rocks, flamingos and the Moon Valley await in Chile
Our South America expert, Scarlett

Our Expert Tip

”Try the canopy walkway in the Amazon (if you have a head for heights), to get a birds-eye view of the thick rainforest and its unique inhabitants”

Scarlett, South America Expert


Day 1-2: Lima, Peru

Catch your international flight into Lima to start your incredible South America trip. Stay at Casa República, in the arty Barranco district, where you can explore independently on foot. Rest up after your journey and perhaps try one of the city’s renowned restaurants.

The next day, with your private guide, choose from an artist walking tour, a street food excursion or a fascinating art and history tour. For more ideas, see our best foodie experiences in Peru.

Lima, the incredible capital of Peru
Wildlife in the Amazon Rainforest

Day 3-5: The Amazon, Peru

Your wildlife adventure begins today, as you fly into the heart of the Amazon at Puerto Maldonado, known in Peru as its capital of biodiversity. Begin with a boat ride along the clay-coloured Madre de Dios River to reach your riverside rainforest lodge.


At dusk, witness the dramatic transformation of the rainforest from a diurnal to a nocturnal environment on a guided twilight river boat ride, as the animals and birds of the daytime give way to species specially adapted to the shadows of the night. Spot caimans lurking on the riverbanks and the dazzling stars of the southern hemisphere.

Your days here are filled with incredible wildlife excursions. Visit Lake Sandoval by dug-out canoe and quietly paddle past picture-perfect rainforest. Look out for a variety of bird species, the endangered giant river otter, red howler monkeys, red-bellied macaws, anacondas, side-neck turtles and black caimans, among others. With your guide, enjoy rainforest trails that bring you closer to nature, and scale the canopy walkways looking for bright toucans, woodpeckers, trogons, monkeys and the three-toed sloth.

Day 6-7: Sacred Valley, Peru

Enjoy your last morning waking to the sounds of the rainforest before boarding motorised wooden boats for your return journey to the airport, then fly to Cusco and transfer to Las Casitas del Arco Iris or similar in the Sacred Valley. Being at a lower altitude than Cusco, the acclimatisation process will be a little quicker and easier.

The Sacred Valley is teeming with amazing sights and activities. Explore the three jewels of the Inca Sacred Valley (Maras, Moray and Misminay) and take in majestic views of the ancient Maras salt mines and archaeological sites that resemble natural amphitheatres.

For a unique cultural highlight, visit the traditional community of Misminay to experience an authentic cultural exchange and gain a closer insight into the traditional Andean lifestyle. You’ll be invited to take part in daily activities such as planting, harvesting and textile weaving.

Peru cultural activities with the Misminay community
Enjoy some incredible hikes in Peru with Travel Differently

Day 8: Ollantaytambo & Pachamanca, Peru

Continue to the Ollantaytambo ruins and explore this truly impressive archaeological complex, strategically perched atop a mountain that once guarded the road to Machu Picchu.

Ollantaytambo, built by the Inca Pachacuti, is remarkable for having preserved its original Inca design within the modern-day urban layout. Enjoy a traditional Pachamanca lunch, where you’ll learn about this ancient earth-oven cooking method: watch as hot stones are layered with meats, tubers and local ingredients, then covered with leaves and earth to cook slowly beneath the surface.

Catch a train for a beautiful journey to Machu Picchu Pueblo, travelling alongside the Vilcanota River, for two nights at El MaPi.

Day 9: Machu Picchu, Peru

Take a bus up to the gates of Machu Picchu to begin your exploration of one of the true Wonders of the World. Wander among the ruins and terraces as you learn about the history of this remarkable site and the wider Inca civilisation.

Witness the amazing engineering skills still visible and marvel at the sight of ancient buildings clinging to the mountainside: a true highlight of any trip to Peru. Prefer to arrive on foot? Read our guide to hiking in Peru.

Explore Machu Picchu on one of our incredible sabbatical holidays
Cathedral Cusco

Day 10: Cusco, Peru

Travel back by train and road to Cusco, the former capital of the Inca Empire, for a night at Quinta San Blas.

With your expert guide, start at the Plaza de Armas and walk to Koricancha, where Spanish builders raised a church on top of the Incas’ finest stonework. Then drive up above the city to the zigzag walls of Sacsayhuamán and the carved rock shrine of Q’enqo, before an evening at one of Cusco’s excellent restaurants.

Day 11: Puno, Peru

Leave for Puno, taking in the wonderful landscapes of the Southern Valley of Cusco along the way. Your first stop is Andahuaylillas, home to the Church of San Pedro, beautifully decorated with angels and cherubs.

Continue to the Raqchi ruins, also known as the Temple of the God Wiracocha, before heading to La Raya, the highest point between Cusco and Puno, where you’ll make a short stop to admire the breathtaking scenery.

Relax after a busy few days of exploration.

Visit Puno, in Peru
Kayak on Lake Titicaca Peru

Day 12: Lake Titicaca, Peru

Your Lake Titicaca adventure begins at Huayllano, the lake dock for the island of Taquile. Boarding a speedboat, head towards this beautiful island, where locals will be waiting to invite you into their homes to learn about their day-to-day activities and traditions, such as weaving. Learn from skilful craftsmen who use ancestral techniques passed down through generations.

Enjoy a delicious lunch featuring local ingredients before boarding the speedboat once more. Stop at the famous floating islands of the Uros, built from bundles of totora reed, where you’ll learn about the islanders’ way of life and enjoy the serene sights. Prefer to paddle? Our Slow Travel Peru holiday explores the lake by kayak.

Day 13-14: La Paz, Bolivia

Saying farewell to Peru, your adventure continues into Bolivia. Be driven (around 8 hours, with comfort stops) along the shores of the lake towards La Paz, stopping off at Copacabana, one of the towns on the Bolivian side of the lake. With your local expert guide, discover the highlights of La Paz.

Begin in the strange, eroded landscape of the Valley of the Moon, then take a breathtaking ride on the cable cars from La Paz to El Alto, with unparalleled views of the city and the majestic Cordillera Real mountains. Enjoy a walking tour along Calle Jaén, Plaza Murillo and San Francisco Church, ending at the enchanting Witches’ Market.

La Paz, Bolivia
The other-worldly Salt flats in Bolivia

Day 15-16: Salar de Uyuni, Bolivia

Fly to Uyuni, on the edge of the world-famous salt flats. Hop into your privately driven 4×4, which will be your vehicle for the next four days of adventure. Visit the eerie Train Cemetery, where the rusting remains of old locomotives tell stories of a bygone era, before entering the vast Uyuni Salt Flats. En route, see a traditional salt-processing plant.

Continue with visits to Ojos de Agua and Incahuasi Island, home to the famous giant cacti. Pause to take in the breathtaking sunset over the dazzling white expanse of the Uyuni Salt Flats.

On your second day, visit San Cristóbal, with its charming colonial church, and explore the Valley of the Rocks, where dramatic formations have been sculpted by centuries of wind erosion. Journey on to the Catal and Vinto Lagoons and marvel at the striking rock formation known as Italia Perdida (“Lost Italy”).

Day 17-20: Atacama Desert, chile

Your South American odyssey continues into Chile. Begin with a visit to Laguna Colorada, home to the famous colour-changing James’s flamingos, and the Sol de Mañana geysers, passing through hot springs on your way to Laguna Verde, at the foot of the Licancabur Volcano.

Enjoy lunch in the desert before crossing into Chile and continuing to San Pedro de Atacama, where you’ll stay at La Casa de Don Tomás.

We’ve included four full days here to fully explore everything this remarkable red rock desert has to offer, from hiking, biking and trekking to jeep tours, culminating with a visit to the iconic Moon Valley. For more ideas, see the best things to do in the Atacama Desert.

Enjoy exploring the Atacama Desert in Chile
The capital of Chile, Santiago

Day 21: Santiago, Chile

As your adventure comes to an end, catch your flight to Santiago for a final night at Rugendas Hotel Boutique or similar. Relax after your thrilling activities, enjoy some delicious food and wine from one of the many quality restaurants in the city, or explore some of Santiago’s fascinating museums. If you’re interested in extending your trip to include Patagonia, or a visit to a wine region, take a look at our other Chile holidays and speak to our experts to find out more.

Day 22: Departure

Transfer to Santiago airport for your flight home. Prefer to focus on one country? Browse all our tailor-made Peru holidays.

When to Go

Best time for a Peru, Bolivia and Chile holiday

The best time for this trip is May to October, the dry season in the Andes and on the altiplano, with clear skies at Machu Picchu, on Lake Titicaca and across the salt flats. From January to March, rain on the Uyuni salt flats can create the famous mirror effect, though some routes may be closed. The Amazon and the Atacama can be visited all year. Nights on the altiplano are very cold, especially from June to August.

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